Kelly Ripa appeared grief stricken on Live! With Kelly and Michael on Tuesday.

“He was such a great man… he was just a great person, a great friend, he will be missed–I cannot tell you how much I will miss him. I will miss him every day of my life,” she said while on the air.

Cosmetic surgeon Dr Fredric Brandt was found dead by suicide inside his Miami mansion on Sunday. Kelly Ripa had long been among his celebrity clients–and dear friends.

“If you love someone tell them every day that you love them because you don’t know if you will have that opportunity….It’s sad. Oh my gosh, he was just the best. He would sing to you while he put Botox in your face–any song you wanted. He could sing anything at a moment’s notice,” she said.

On Monday, Kelly Ripa tweeted her heartache upon learning that Dr. Brandt had died over the weekend.

My heart is breaking for the loss of Dr. Fredric Brandt. My friend. You will be missed forever and in my heart even longer.

— Kelly Ripa (@KellyRipa) April 6, 2015

It is with heavy hearts and deep sorrow that we say goodbye to our beloved Dr. Fredric Brandt.… https://t.co/E7rxpHslFo

— Dr. Brandt (@drfredricbrandt) April 6, 2015

Kelly’s husband, Mark Consuelos, retweeted sentiments about the plastic surgeon’s passing.

Devastated over the loss of our dear friend @drfredricbrandt You are missed. You are loved. The world has lost one of its kindest souls

— Isaac Calpito (@isaacboots) April 6, 2015

In addition to Kelly Ripa, some of Dr. Frederic Brandt’s other celebrity clients included Madonna and Joy Behar. There were, of course, numerous others.

A photo posted by Dr. Brandt (@drbrandt) on Apr 6, 2015 at 1:18pm PDT

Suicide is probably the hardest type of death for survivors to accept. Dr. Brandt’s family members and his beloved clients–like Kelly Ripa–will no doubt always wonder what they might have said or done that could have prevented the doctor from taking his life.