Bank of America: S&P 500 November Gains and Top Sector Picks for 2025

As 2025 nears its end, Bank of America highlights November's historical S&P 500 gains (59% positive since 1927, averaging 1%) amid volatility. They recommend investing in tech (AI-driven), healthcare (demographic boosts), and industrials (infrastructure ties) for outperformance. Caution on dips persists, with forecasts eyeing 6,666 by year-end and 8% growth in 2026.
Bank of America: S&P 500 November Gains and Top Sector Picks for 2025
Written by Sara Donnelly

As investors brace for the final stretch of 2025, historical patterns suggest November could deliver a welcome boost to portfolios. According to an analysis by Bank of America, the S&P 500 has gained in 59% of Novembers since 1927, with an average return of 1%. This seasonal tailwind comes amid a year marked by volatility, where the index has flirted with record highs despite economic headwinds like fluctuating interest rates and geopolitical tensions.

Bank of America’s strategists, in a recent report highlighted by Business Insider, recommend focusing on sectors poised for outperformance. Tech, healthcare, and industrials top their list, driven by resilient earnings growth and favorable macroeconomic shifts. For tech, the emphasis is on companies leveraging artificial intelligence and cloud computing, which have shown robust demand even in uncertain times.

Navigating Sector Strengths Amid Economic Shifts

In the tech arena, BofA points to valuations that, while elevated, are supported by strong fundamentals. The sector’s price-to-earnings ratios have climbed, but projected earnings growth for 2026—estimated at 8% for the broader S&P 500—could justify the premiums. Healthcare, meanwhile, benefits from demographic trends like aging populations and innovation in biotech, making it a defensive play with growth potential.

Industrials are favored for their ties to infrastructure spending and manufacturing resurgence. BofA’s outlook aligns with broader market predictions, such as those from Wells Fargo, which in a June 2025 analysis shared via Business Insider, identified similar sectors as likely leaders through year-end volatility. These recommendations come as the S&P 500 eyes potential targets, with BofA forecasting a rise to around 6,666 by year’s end in separate commentary reported by Yahoo Finance.

Historical Patterns and Forward-Looking Risks

Yet, caution is warranted. Technical indicators have flashed warnings of possible dips, as noted in a September 2025 Business Insider piece on BofA’s analysis, where signals like overbought conditions suggest short-term pullbacks. Investors are advised to buy such dips, a strategy that has paid off this year, with the index rebounding to records after steep drops.

For industry insiders, the key lies in diversification within these sectors. In tech, firms with AI exposure like Nvidia have surged, contributing to Nasdaq’s six straight winning sessions in May 2025, per Investopedia. Healthcare stocks offer stability through regulatory tailwinds, while industrials could thrive on policy-driven investments, such as those anticipated under potential tariff regimes.

Strategic Allocation for 2026 and Beyond

Looking ahead, BofA’s 8% growth prediction for the S&P 500 in 2026 underscores the importance of large-cap value stocks leading the charge, as detailed in their September 2025 outlook via Business Insider. This broadening rally beyond megacaps could benefit healthcare and industrials, sectors less prone to the valuation bubbles seen in tech, where price-to-book metrics hit historic highs in August 2025, according to BofA warnings in another Business Insider report.

Goldman Sachs, in a November 2024 strategy note covered by Business Insider, echoes this by highlighting four investment themes to outperform the market in 2025, including growth-oriented industrials and tech innovators. For insiders, timing entries around November’s historical strength—coupled with monitoring key levels like the S&P’s 6,200 support, as flagged by BofA in August 2025—could optimize returns.

Balancing Optimism with Vigilance in Volatile Times

Ultimately, while November’s track record offers optimism, the path forward hinges on corporate earnings resilience. Schwab’s monthly sector outlook, updated in October 2025, reinforces healthcare and industrials as strong performers amid energy and consumer shifts. Investors should watch for economic data releases that could sway sentiment, ensuring allocations align with long-term trends rather than short-term noise.

As the year closes, these sector bets from BofA provide a roadmap for navigating uncertainty, blending historical data with forward projections to guide sophisticated portfolios toward sustained growth.

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