As artificial intelligence enters its most commercial phase yet, OpenAI and Anthropic are locking horns over lucrative enterprise contracts, with both companies pitching advanced tools at the World Economic Forum in Davos. Enterprise revenue now drives roughly 40% of OpenAI’s business and a staggering 80% of Anthropic’s, according to executives speaking at the gathering. This shift underscores the pressure on AI labs to convert cutting-edge models into steady cash flows amid soaring compute costs and investor scrutiny.

Davos Signals Shift to Big Business

At Davos, OpenAI’s chief strategy officer Jason Kwon emphasized the company’s focus on ‘deepening our enterprise relationships,’ while Anthropic CEO Dario Amodei highlighted plans to scale AI deployments for Fortune 500 firms. CNBC reported that both firms see corporate clients as key to sustainability, with OpenAI targeting sectors like finance and healthcare, and Anthropic pushing its Claude models into regulated industries.

The competition intensified as Anthropic unveiled ‘Agent Skills,’ an open framework for AI agents that has drawn adopters including Microsoft, OpenAI itself, Atlassian, and Figma. This move challenges OpenAI’s dominance in workplace AI, per VentureBeat, positioning Anthropic as a standard-setter for enterprise automation.

Revenue Pressures Mount in 2026

Anthropic recently slashed its 2025 gross margin forecast to 40% from 50%, citing exploding AI inference costs, while projecting revenue to balloon from $1 billion in 2024 to $10 billion in 2025 and $26 billion by 2026. WebProNews noted this reflects broader industry strains, with OpenAI facing a similar ‘reckoning’ as investors demand profitability. OpenAI’s CFO Sarah Friar discussed compute scarcity on the company podcast, warning that demand outstrips supply.

OpenAI and Anthropic are eyeing healthcare as a prime battleground. Anthropic’s Claude for Healthcare launch has rattled software investors, per Business Insider, while both firms position AI as the next frontier. A Bloomberg newsletter highlighted executives’ optimism for regulatory breakthroughs enabling widespread adoption.

Strategic Partnerships Fuel Expansion

Anthropic expanded its tie-up with Accenture, training 30,000 professionals on Claude and launching tools for CIOs to scale code generation. Posts on X from Anthropic detailed the Accenture Anthropic Business Group, aimed at moving enterprises from pilots to production. Meanwhile, OpenAI predicts 2026 progress will hinge on user enablement, not just model advances, as stated in a company post.

Anthropic’s enterprise search feature integrates company knowledge into Claude projects, boosting adoption among Team and Enterprise users. ZDNet surveys show Anthropic quietly gaining ground in enterprise AI, with agentic tools still niche but growing. OpenAI counters with custom integrations for financial data, as seen in recent financial services announcements.

IPO Speculation Adds Urgency

Wall Street buzzes with talk of mega-IPOs in 2026, potentially including OpenAI and Anthropic alongside SpaceX. The New York Times reports these listings could flood Silicon Valley with cash, but only if profitability materializes. Anthropic’s $13 billion raise at a $183 billion valuation, announced on X, funds capacity and safety research amid the race.

Enterprise focus addresses high costs: OpenAI’s WebProNews analysis warns of shifts to ads, enterprise software, and agents. Tekedia frames this as a ‘commercially disciplined phase,’ with both firms locking in multi-year deals to weather compute shortages.

Product Innovations Tip the Scales

Anthropic’s Integrations and Research betas for enterprise plans enable custom tool-building, soon extending to Pro users. Healthcare and finance connectors, plus MCP for data providers, target high-value clients. OpenAI’s podcast with Khosla Ventures’ Vinod Khosla, shared on X, stressed equitable AI access through enterprise scaling.

Menlo Ventures’ survey via ZDNet reveals Anthropic’s edge in select verticals, though Google looms large. Seeking Alpha notes both firms racing for revenue and market share, with Davos deals accelerating momentum.

Path to Dominance Hinges on Execution

As 2026 unfolds, execution on enterprise promises will define winners. Anthropic’s engineering blog detailed redesigning performance exams after Claude Opus 4.5 outperformed humans, signaling rapid capability leaps. Partnerships like Teach For All for educators show broader ambitions, but corporate boardrooms remain the prize.